AXIS BRAIN FLOW™

NEUTRAL. CIRCULATION. ENERGY.

The Brain Reset Protocol for high performers who feel foggy, flat, and fried. 

You’re sipping coffee past 3PM - knowing it’ll wreck your sleep.

You’re on your third nootropic stack this week and your brain still feels fried.

You’re vaping between Zoom calls just to stay alert.

You’re not lazy. You’re overloaded.

You don’t need more stimulants or hype. You need your brain’s grid rebuilt.

Think of mental clarity like a city power system:

  1. Neural Connections - the communication lines that carry signals between brain regions.
  2. Circulation - the pipelines delivering oxygen and nutrients to fuel those signals.
  3. Energy Infrastructure - the mitochondrial “batteries” powering every thought.

When one system short-circuits, you brown out.

When all three collapse, you crash.

When all three come online, you don’t just think, you flow.

3 SUPER-INGREDIENTS

NAD+ (500 mg)

Lion’s Mane Mushroom (Hericium erinaceus)

Creatine Monohydrate (5 g)

NAD+ (500 mg)

Role: Recharges your brain’s mitochondrial “batteries” so neurons can fire without fading.

The simple story:

NAD⁺ isn’t a precursor - it’s the actual molecule your neurons use to produce ATP, the fuel for cognitive effort. When NAD⁺ runs low from chronic stress, long hours, or aging, your brain’s energy grid flickers: clarity fades, focus shortens, and mental stamina breaks down.


By restoring NAD⁺ directly and shielding it with quercetin (slows NAD⁺ breakdown) and resveratrol (signals cell renewal). AXIS BRAIN FLOW™ helps your brain stop sputtering and start running on full charge.

Science in plain English:

  • In animal studies, NAD⁺ supplementation improved cognitive performance, reduced brain inflammation, protected mitochondria, and reactivated cellular energy pathways — even in stressed brains with impaired blood flow.

  • In a 2021 study, rats given NAD⁺ showed better memory, reduced oxidative stress, and activation of brain-repair enzymes like SIRT1 and PGC‑1α (Zhao et al., 2021, Journal of Neuroinflammation)

  • A 2022 follow-up in mice confirmed similar results: less brain damage, better neurological scores, and stronger mitochondrial protection after cerebral injury (Chen et al., 2022, Nutrients)


These findings suggest that NAD⁺ helps the brain maintain energy under pressure, whether from chronic workload, lack of sleep, or cognitive fatigue.


AXIS WELLNESS Metaphor:

If your phone kept dying at 2 PM, you wouldn’t download new apps: you’d fix the battery. NAD⁺ is that battery. Resveratrol and quercetin are the guards that protect its charge, helping your neurons stay online, focused, and firing long after others start crashing.

Lion’s Mane Mushroom (Hericium erinaceus)

Role: Sparks Nerve Growth Factor (NGF): new synaptic wiring for memory, focus, creativity.

The simple story:

Lion’s Mane triggers the production of NGF, which supports the formation of new neural pathways. Think of it as “mental wiring”: more NGF = stronger, faster connections between brain regions = improved learning, recall, and creative flow.

Science in plain English:

Lion’s Mane stimulates NGF synthesis, which is essential for neuron growth and synaptic plasticity. Human studies show significant cognitive improvements in older adults and neurotypical individuals. Its neurotrophic effects are thought to enhance signal transmission and protect against cognitive decline.

  • In a 2009 double-blind, placebo-controlled trial, older adults with mild cognitive impairment who took Lion’s Mane daily for 16 weeks showed significant improvements in memory and cognitive function — with scores declining after stopping the supplement (Mori et al., 2009, Phytotherapy Research).

  • A 2023 review of animal and human data found that Lion’s Mane stimulates nerve growth factor (NGF), enhances neuroplasticity, and supports learning and memory through synaptic regeneration and brain-cell repair pathways (Zhang et al., 2023, Nutrients).


AXIS WELLNESS Metaphor: 

It’s like upgrading from DSL to fiber optic. Lion’s Mane lays new cable between your brain’s decision centers. Everything loads faster.

Creatine Monohydrate (5 g)

Role: Provides backup ATP when neurons are under load — decision marathons, red-eye flights, back-to-back meetings.

The simple story:

Creatine stores phosphate bonds that can quickly regenerate ATP in your brain. When neural demand spikes (cognitive stress, poor sleep), creatine buffers energy loss and sustains mental output.

Science in plain English:

Creatine enhances brain bioenergetics, especially under stress. Meta-analyses confirm improved short-term memory, processing speed, and reduced fatigue during cognitive tasks — particularly under sleep deprivation or emotional strain.

  • In a 2023 meta‑analysis of healthy adults, creatine monohydrate supplementation showed significant boosts in memory, faster attention, and improved processing speed (Sandkühler et al., 2023, Frontiers in Nutrition)

  • A 2003 young‑adult RCT - 5 g/day for 6 weeks - found vegetarians given creatine scored notably higher on working memory (Backwards Digit Span) and intelligence tests (Raven’s APM) (Rae et al., 2003)

  • Under sleep deprivation (24+ h), creatine supplementation helped preserve performance on choice reaction time, working memory, and mood compared to placebo, especially on cognitively demanding tasks (McMorris et al., 2006) 


AXIS WELLNESS Metaphor:

NAD+ is the charger. Creatine is the portable power bank that kicks in when life gets heavy.

THE SUPPORT CAST

Why the rest of your formula matters

Ginkgo Biloba + Ginseng - The Circulation Duo

Resveratrol — The NAD⁺ Amplifier

Quercetin — The Absorption Booster

Adaptogenic Mushroom Complex (Cordyceps, Reishi, Chaga, Maitake)

Ginkgo Biloba + Ginseng - The Circulation Duo

What you feel: Faster thinking. Smoother mental transitions. No more cognitive bottlenecks after long hours or multitasking marathons.


How it works: Cognition isn’t just about neurons - it’s about flow. When oxygen, glucose, and brain-boosting nutrients don’t reach your frontal cortex fast enough, mental power stalls. Ginkgo and Ginseng work together to restore that flow:

  • Ginkgo improves cerebral blood flow, delivering oxygen and glucose more efficiently to brain cells.
  • Ginseng supports working memory, lowers perceived fatigue, and buffers mental stress.

Together, they optimize both delivery and endurance so your focus holds, memory sharpens, and your mind stays online even after a hard push.

Science in Plain English:

  • In a 2002 crossover trial, single doses of Ginkgo biloba (120 mg), Panax ginseng (200 mg), and their combination significantly improved memory performance, attention accuracy, and mental arithmetic in healthy young adults. Notably, effects were strongest later in the day, when mental fatigue tends to build (Kennedy et al., 2002, Physiology & Behavior).

  • A 2005 randomized, double-blind, placebo-controlled study showed that a single dose of ginseng (400 mg) improved mental arithmetic accuracy and reduced mental fatigue during prolonged cognitive tasks (Reay et al., 2005, Appetite).

AXIS WELLNESS Metaphor:

Think of your brain like a high-performance office tower. Ginkgo widens the pipes so more oxygen and nutrients get delivered to every floor. Ginseng boosts the internal pressure so the flow keeps going strong under load. Together, they remove the bottlenecks that make your thoughts feel sluggish, slow, or foggy, especially late in the day.

Resveratrol — The NAD⁺ Amplifier

What you feel: More mental stamina, clearer focus past dusk, fewer dips when hours drag on. You still feel sharp when others slow down.

  • Late‑evening mental fatigue? Stays away longer.
  • Long work sessions? You maintain clarity instead of fading.
  • Burnout from pushing too hard? You buffer it, recover better.


How it works: Resveratrol helps amplify your brain’s repair systems. It supports enzymes that depend on NAD⁺ (like SIRT1) to:

  1. Repair cellular damage
  2. Boost mitochondrial function (your cell’s batteries)
  3. Support metabolic resilience so energy delivery stays strong under stress

  • In effect, it makes every dose of NAD⁺ work harder and last longer. It helps protect your energy baseline so fatigue doesn’t sneak in early.

Science in Plain English:

  • In a 2006 study, middle‑aged mice on a high‑calorie diet given resveratrol showed improved insulin sensitivity, increased mitochondrial number, better motor function, and changes in gene activity (PGC‑1α, AMPK) that reversed many signs of metabolic stress. (Baur et al., 2006, Nature)

  • In a landmark 2006 study, resveratrol activated SIRT1 and PGC‑1α in mice, improving mitochondrial function and oxidative capacity, especially in muscle tissue, leading to better energy metabolism and protection against metabolic disease. (Lagouge et al., 2006, Cell)

AXIS WELLNESS Metaphor:

Think of your brain like a race car: NAD⁺ is the fuel in the tank; Resveratrol is the high‑performance additive that cleans the fuel lines, improves mileage, and keeps the engine running smooth under heat. Without Resveratrol, fuel wastes away; with it, your engine (brain) runs cleaner, longer, harder.

Quercetin — The Absorption Booster

What you feel: More consistent energy. Fewer dips. The kind of mental output that lasts from early morning through late evening without crashing.

  • You don’t fade at 3 PM. You keep pushing without that “brain‑drag” setting in.
  • Stress and long hours hit differently, less shakiness, less crash.
  • Your mental battery lasts, so you’re still sharp in evening work, creative after hours, and still capable when others have checked out.


How it works:

  • Quercetin helps protect your NAD⁺ levels by inhibiting CD38, the enzyme that burns through NAD⁺ and with CD38 suppressed, more NAD⁺ stays available for repair processes, mitochondrial energy production, and maintaining clarity under stress.
  • The result? When paired with your NAD⁺ intake, quercetin makes your energy baseline stronger and more resilient, meaning focus holds longer, recovery happens quietly, and fatigue doesn’t sneak in first.

Science in Plain English:

  • CD38 is one of the main NAD⁺-consuming enzymes in mammals. Its activity increases with stress and age, leading to faster NAD⁺ depletion and mitochondrial dysfunction. Inhibiting CD38 has been shown to preserve NAD⁺ and improve energy metabolism in multiple tissues (Camacho-Pereira et al., 2016, Cell Metabolism).

  • Quercetin is a natural flavonoid that helps protect your NAD⁺ levels by inhibiting CD38 — the enzyme that breaks down NAD⁺ during stress and inflammation. In immune cells, quercetin has been shown to reduce CD38 expression, preserve NAD⁺, and support mitochondrial energy output under stress (Chini et al., 2019, Frontiers in Immunology).


AXIS WELLNESS Metaphor:

Think of your energy as a fire burning in two parts: fuel and haul. NAD⁺ is your fuel; CD38 is like a leak in the fuel line, letting power drip away when you need it most. Quercetin plugs the leak, so the fuel (NAD⁺) stays in the tank longer, the fire holds strong, and you finish the day lit, not flickering.

Adaptogenic Mushroom Complex (Cordyceps, Reishi, Chaga, Maitake)

What you feel: Less frazzled. More even‑keeled. That moment when the stress pile‑up still happens, but you don’t lose it. Clarity returns even when pressure builds.

How it works: Adaptogenic fungi bring a mix of immune modulation, neuroprotection, and anti‑inflammation. They help:

  • Soothe low‑grade inflammation so mental clarity isn’t eaten alive
  • Boost resilience to stress, especially in long work or disruption phases
  • Support brain health by protecting neurons, supporting antioxidant defenses, and improving mitochondrial performance under stress

Science in Plain English:

  • A human macrophage study revealed that blends of Reishi, Shiitake, and Maitake mushroom extracts have potent immunomodulatory activity. Extracts reduced expression of inflammatory cytokines IL‑1α, IL‑6, TNF‑α, and increased IL‑10 in both stimulated and non‑stimulated immune cells. This means they help calm immune over‑reaction (which is one source of brain fog and low energy). (Mallard et al., PLOS ONE)

  • Cordyceps militaris has been shown in rodent studies to improve cognitive performance and reduce oxidative stress / neuroinflammation. One aged rat study combining Cordyceps + alpha‑lipoic acid showed lower oxidative markers, better performance on memory & learning tasks under stress. (SAGE Journals)

AXIS WELLNESS Metaphor:

Think of your brain as a concert hall. Cordyceps, Reishi, Maitake, and Chaga are your acoustic engineers, soundproofing the hall against noise (inflammation), tuning the walls (immune response), cleaning out the ducts (oxidative stress). So you don’t just survive; you perform cleanly, even when the show runs late.

Axis Brain Flow Transformation

Adapt

Flow

Fuel

Vitality

From Fire-Fight Mode to Adaptive Flow

When your stress system is locked in fight-or-flight, even small pressures feel like overload. Your mind races, your body tenses, and energy burns hot then crashes… leaving you wired, tired, and reactive. 

But when your system learns to adapt, everything changes. Your breath deepens, focus steadies, and energy flows clean instead of spiking. You start moving through the day grounded and responsive, calm in the chaos, clear under pressure, and steady from the inside out.

Before

After

From Afternoon Fog → All-Day Flow

When your brain’s blood flow slows, focus feels like pushing through fog: words blur, energy drops, and every task feels heavier. But when your circulation opens, oxygen flows freely again. Thought becomes effortless. Your energy feels clean, your focus sharpens, and your mind hums from morning to night: steady, clear, alive.

Before

After

From Midday Crash → Cellular Power

When your cells run low on energy, it’s not just your body that slows down… your mind does too. That foggy fatigue you feel mid-afternoon? That’s a cellular power outage. AXIS FUEL recharges your mitochondria, the energy factories in your cells so you can think sharper, perform stronger, and stay switched on all day.

Before

After

From Running on Empty to Recharged at Your Core.

When your cells are starved of energy, you feel it everywhere… your focus drifts, recovery slows, and motivation fades. You wake up already running on half a charge, chasing energy that never seems to last.

But when your cells are recharged with NAD+, everything changes. Your mornings start clear, your body feels younger, and your mind stays lit with quiet endurance. It’s not a burst… It's a steady current of energy that carries you through the day and the decades ahead.

Before

After

Result:mornings start bright, no 2:30 wall, evenings feel calm and focused. Not a stim surge - a new baseline.

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What to Expect: The AXIS Brain Flow Reset Timeline

  • Week 1–3

    Less fog after lunch. Your brain actually holds what you just read. Tasks feel more manageable. Even under pressure, your brain feels more “available.”

  • Week 4–7

    Sharper memory: you recall names, topics, tasks without looping back. Decisions feel lighter: fewer seconds between thought and action. Energy holds without leaning on stimulants.

  • Week 7–10

    Mornings feel less rigid. Mental flow pushes through til evening. Tasks you used to dread feel doable. Dinner conversation doesn’t feel like mental sludge.

  • Week 10–12+

    Flow becomes your default. You don’t chase sharpness, it’s just there. You lead meetings, spark creativity, juggle high‑pressure moments, and you still have fuel left.

You’ve been trying to outwork a biological bottleneck which is like trying to win a marathon while running in ankle weights.

AXIS BRAIN FLOW™ hands your brain the blueprint it lost:

  • Recharge the batteries. (NAD + Creatine)
  • Lay new wiring. (Lion’s Mane + NGF)
  • Improve circulation. (Ginkgo + Ginseng)

When the batteries stay full and the wiring holds, you stop living in mental brownouts. The fog lifts. Decisions sharpen. Evenings feel alive again.

Not another stim.

Not a hack.

Just the stimulant-free cognitive power you built your life on.

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FAQs

Isn’t this just another nootropic?

No. Most nootropics stimulate neurotransmitters (like dopamine). AXIS BRAIN FLOW™ rebuilds the entire system: energy, wiring, and delivery from the ground up.

Will I actually feel it?

✅ Week 1–2: Less rereading. Fewer dips. The fog starts to lift.

✅ Week 3–4: Your edge returns. You catch things quicker. Decisions feel cleaner.

✅ Week 5–6: Energy holds through high-stakes days — without a stimulant crutch.

Can I still drink coffee?

Of course. But most users report they no longer need the 3 PM cup to survive. Coffee becomes a ritual - not a rescue and this is when that coffee feels goooood!!